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Lodenafil
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lodenafil图片
CAS NO:139755-85-4
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Hydroxyhomosildenafil
羟基豪莫西地那非
产品介绍
Lodenafil 是一种有效的磷酸二酯酶 5 型(PDE5)抑制剂,可用于勃起功能障碍的研究。

产品描述

Lodenafil is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)

体内活性

Investigated right ventricular hypertrophy (RVH) and IL-1 levels in lung fragments. The number of cases of RVH was significantly higher in the monocrotaline group than in the lodenafil and control groups, as were mPAP and IL-1 levels. Lodenafil can prevent monocrotaline-induced PH, RVH, and inflammation[1].

动物实验

Thirty male Sprague-Dawley rats were randomly divided into three groups: control; monocrotaline (experimental model); and lodenafil (experimental model followed by lodenafil treatment, 5 mg/kg daily for 28 days) Mean pulmonary artery pressure (mPAP) was obtained by right heart catheterization[1].

Cas No.

139755-85-4

分子式

C23H32N6O5S

分子量

504.61

别名

Hydroxyhomosildenafil;羟基豪莫西地那非;Lodenafil

储存和溶解度

DMSO:250 mg/mL (495.44 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years