NGB2904 HCl 是一种具有口服活性的、选择性的多巴胺(DA) D3受体拮抗剂,可用于具可卡因成瘾。
产品描述
NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, >5000, >10000 and >10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
Cas No.
189060-98-8
分子式
C28H29Cl2N3O
分子量
494.45
别名
NGB2904;NGB2904 HCl;NGB-2904;NGB 2904
储存和溶解度
DMSO:16.25 mg/ml (30.61 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years