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SKF-82958 hydrobromide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SKF-82958 hydrobromide图片
CAS NO:74115-01-8
包装:100 mg
市场价:9417元

产品名称
Chloro-APB hydrobromide
(±)-SKF 82958 hydrobromide
产品介绍

产品描述

SKF-82958 hydrobromide is a D1/D5 receptor full agonist.

体外活性

Neuropeptide and immediate early gene expression in striatonigral neurons of the normotensive striatum is induced by mixed D1 receptor SKF-82958, which induces behavioral activity and preprodynorphin (PPD) and substance P (SP) gene expression in medium spiny neurons in the dorsal, and especially, in the ventral striatum.

体内活性

Quantitative in situ hybridization was used to examine the contribution of muscarinic receptors to the transsynaptic regulation of striatal gene expression induced by D1receptor activation. The acute injection of the full D1 agonist, SKF-82958, would induce PPD, SP, and PPE mRNA expression in the intact rat striatum.

Cas No.

74115-01-8

分子式

C19H21BrClNO2

分子量

410.73

别名

Chloro-APB hydrobromide;(±)-SKF 82958 hydrobromide;SKF-82958 hydrobromide

储存和溶解度

DMSO:102.5 mg/mL (249.56 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years