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AS19
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AS19图片
CAS NO:1000578-26-6
包装:10 mg
市场价:7781元

产品介绍

产品描述

AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively).

体外活性

The proliferation of T-cells from parachlorophenylalanine-treated mice is significantly reduced, the addition of AS19 (1 μM) completely restores T-cell proliferation after 48 hours [2].

体内活性

AS19 (0.5-10 mg/kg; subcutaneous injection; for 24 hours; male Wistar rats) treatment improves memory consolidation in an autoshaping Pavlovian/instrumental learning task [1].

Cas No.

1000578-26-6

分子式

C18H25N3

分子量

283.41

别名

AS19

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years