SR59230A 是可透过血脑屏障的、选择性的 β3-肾上腺素能受体拮抗剂，对 β3，β1 和 β2 受体的IC50分别为 40、408 和 648 nM。

SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).

The specific antagonism of β3-AR by SR59230A inhibits NB growth and tumor progression, by switching from stemness to cell differentiation both in vivo and in vitro through the specific blockade of SK2/S1P2?signaling[1].

174689-39-5

C23H29NO6

415.48

SR59230A

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years