GR 103691 是选择性的多巴胺 D3受体拮抗剂，Ki=0.4 nM。它对人多巴胺 D3的选择性超过 D4和 D1的 100 倍以上。

GR 103691 is a potent, selective dopamine D3 receptor antagonist (Ki: 0.4 nM). It shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.

GR 103691 shows a marked affinity for α-1 adrenoceptors (Ki: 12.6 nM) and ?serotonin1A (5-HT1A) receptors (Ki: 5.8 nM).

162408-66-4

C30H35N3O3

485.62

GR 103691

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years