Clocapramine is a D2 and 5-HT2A receptors antagonist.

In vitro, Clocapramine shows a higher affinity for 5-HT2A than for D2-receptors and has a moderate affinity for D2-receptors.

Clocapramine shows the lowest potency for D2-occupancy in vivo [1]. Clocapramine produces ratios of potency in occupying 5-HT2 versus D2 receptors that fall between these two groups (ED50: 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2) [2].

47739-98-0

C28H37ClN4O

481.07

3-Chlorocarpipramine;Clocarpramine;Clocapramine

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years