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L-DABA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-DABA图片
CAS NO:1758-80-1
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品名称
L-2,4-二氨基丁酸氢溴酸盐
L-DAB HBR
L-2,4-Diaminobutyric acid
产品介绍
L-DABA 是GABA转氨酶的弱抑制剂,IC50值大于500 μM,具有抗肿瘤活性。

产品描述

L-DAB HBR is an inhibitor of GABA transaminase (IC50 >500 μM).

体外活性

L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1].

Cas No.

1758-80-1

分子式

C4H10N2O2

分子量

118.136

别名

L-2,4-二氨基丁酸氢溴酸盐;L-DAB HBR;L-2,4-Diaminobutyric acid;L-DABA

储存和溶解度

H2O:Insoluble
DMSO:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years