Homocarnosine acetate 是大脑特有的二肽,由 γ-氨基丁酸 (GABA) 和组氨酸组成。它具有抗氧化和抗炎作用、预防 DNA 损伤和抑制晚期糖基化终产物形成
产品描述
Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation
体外活性
Homocarnosine acetate possesses greater tolerance to degradation by serum carnosinase relative to Carnosine. Homocarnosine acetate is known to be exclusively present in brain and cerebrospinal fluid and acts as a neuroprotective agent in a broad range of disease conditions. Homocarnosine acetate exerts antioxidant activity and prevent DNA oxidative damage to a similar extent as Carnosine[1]. Homocarnosine acetate is composed of γ-aminobutyric acid (GABA) and histidine and has a similar structure to Carnosine, with the only difference being an extra carbon atom in GABA compared to that in β-alanine of carnosine[1].
分子式
C12H20N4O5
分子量
300.31
别名
Homocarnosine acetate
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years