产品描述
BMT-124110 is an effectivet, selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE; IC50: 17 nM) and Cyclin G-associated kinase (GAK; IC50: 99 nM).
体外活性
BMT-124110 shows a cellular IC50 of 3.2 nM for AAK1.
体内活性
BMT-124110 is added directly onto the spinal covered by microiontophoresis, leading to a reduction in windup-induced activity in 10 of 14 animals.
Cas No.
1679371-59-5
分子式
C21H27N3O3
分子量
369.46
别名
BMT-124110
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years