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Ibutilide fumarate(U70226E)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ibutilide fumarate(U70226E)图片
CAS NO:122647-32-9
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
500mg电议
1g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)885.23
Formula(C20H36N2O3S)2.C4H4O4
CAS No.122647-32-9
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 89 mg/mL (100.5 mM)
Water: 89 mg/mL (100.5 mM)
Ethanol: 89 mg/mL (100.5 mM)
Other info

Chemical Name: N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide

InChi Key: ALOBUEHUHMBRLE-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3

SMILES Code: CS(=O)(NC1=CC=C(C(O)CCCN(CC)CCCCCCC)C=C1)=O

SynonymsU70226E; U 70226E; U70226 E; U 70226 E; U-70226-E; U-70226E
实验参考方法
In Vitro

In vitro activity: Ibutilide protected against H2O2-induced cardiomyocytes injury through inhibiting endoplasmic reticulum and mitochondrial stress pathways.

In VivoIbutilide significantly decreased defibrillation threshold through the reduction of activation pattern complexity during ventricular fibrillation in canine hearts.
Animal model
Formulation & Dosage
References

Chin Med J (Engl). 125, 2701-2707.