CAS NO: | 122647-32-9 |
规格: | ≥98% |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
1g | 电议 |
Molecular Weight (MW) | 885.23 |
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Formula | (C20H36N2O3S)2.C4H4O4 |
CAS No. | 122647-32-9 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 89 mg/mL (100.5 mM) |
Water: 89 mg/mL (100.5 mM) | |
Ethanol: 89 mg/mL (100.5 mM) | |
Other info | Chemical Name: N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide InChi Key: ALOBUEHUHMBRLE-UHFFFAOYSA-N InChi Code: InChI=1S/C20H36N2O3S/c1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25/h12-15,20-21,23H,4-11,16-17H2,1-3H3 SMILES Code: CS(=O)(NC1=CC=C(C(O)CCCN(CC)CCCCCCC)C=C1)=O |
Synonyms | U70226E; U 70226E; U70226 E; U 70226 E; U-70226-E; U-70226E |
In Vitro | In vitro activity: Ibutilide protected against H2O2-induced cardiomyocytes injury through inhibiting endoplasmic reticulum and mitochondrial stress pathways. |
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In Vivo | Ibutilide significantly decreased defibrillation threshold through the reduction of activation pattern complexity during ventricular fibrillation in canine hearts. |
Animal model | |
Formulation & Dosage | |
References | Chin Med J (Engl). 125, 2701-2707. |