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Oxotremorine M iodide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxotremorine M iodide图片
CAS NO:3854-04-4
包装与价格:
包装价格(元)
10 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
碘化氧化震颤素M
Oxotremorine methiodide
产品介绍
Oxotremorine M iodide 是 mAChR 的激动剂,可增强 NMDA 受体。

产品描述

Oxotremorine M iodide is an agonist of mAChR and potentiates NMDA receptors.

体外活性

Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM). Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively[1]. Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents[2].

体内活性

In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens[4].

Cas No.

3854-04-4

分子式

C11H19IN2O

分子量

322.19

别名

碘化氧化震颤素M;Oxotremorine methiodide;Oxotremorine M iodide

储存和溶解度

DMSO:100 mg/mL (310.4 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years