Dasatinib N-oxide 是 Dasatinib 的一种次要代谢物。Dasatinib 是口服有效的Src/Bcr-Abl 抑制剂。

Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].

Dasatinib N-oxide is the pharmacologically active metabolite after oral administration[1].

910297-52-8

C22H26ClN7O3S

504.01

Dasatinib N-oxide

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years