Polaprezinc 是口服生物可利用的螯合物,由锌和 L-肌肽组成,具有潜在的胃保护、抗溃疡、抗氧化和抗炎活性。
产品描述
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-ulcer, anti-oxidant and anti-inflammatory activities.
动物实验
Male C57BL/6J mice (8-weeks-old; weight, ~20 g). The mice are acclimated for 7 days. They are housed 4-5/cage and fed a laboratory rodent pellet formula and tap water ad libitum. Mice are maintained at a constant temperature of 22°C±0.5°C, a humidity of 50%±5% and are exposed to 12 h light/dark cycles. The mice orally receive 100 mg/kg body weight Polaprezinc in the drinking water. The mice are irradiated at a dose rate of ~200 cGy/min using a 150 kVp X-ray unit. For dosimetry, a probe connected to an electrometer system is placed close to the target site.
Cas No.
107667-60-7
分子式
C9H12N4O3Zn
分子量
289.6
别名
L-肌肽锌;Zinc L-carnosine;聚普瑞锌;Polaprezinc
储存和溶解度
DMSO:Insoluble
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years