FB23 是FTO去甲基化酶选择性抑制剂(IC50:60 nM)。它能够直接与FTO结合，选择性的抑制FTO的 mRNA N6-甲基腺嘌呤脱甲基酶活性。

FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.)

2243736-35-6

C18H14Cl2N2O3

377.22

FB23

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years