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Dibucaine HCl(Cinchocaine)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dibucaine HCl(Cinchocaine)图片
CAS NO:61-12-1
规格:≥98%
包装与价格:
包装价格(元)
500mg电议
1g电议
2g电议
5g电议
10g电议
100g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)379.92
FormulaC20H29N3O2.HCl
CAS No.61-12-1
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 76 mg/mL (200.0 mM)
Water: 76 mg/mL (200.0 mM)
Ethanol: 76 mg/mL (200.0 mM)
Other info

Chemical Name: 2-Butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide hydrochloride

InChi Key: IVHBBMHQKZBJEU-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H

SMILES Code: O=C(C1=CC(OCCCC)=NC2=CC=CC=C12)NCCN(CC)CC.[H]Cl

SynonymsCinchocaine hydrochloride; Cincaine chloride; Cinchocaine HCl; Dibucaine HCl; Cincain; Nupercainal; Nupercaine; Sovcaine
实验参考方法
In Vitro

In vitro activity: Dibucaine (Cinchocaine) HCl is one of the most potent and toxic of the long-acting local anesthetics. Dibucaine (Cinchocaine) HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

In Vivo
Animal model
Formulation & Dosage
References

Biochim Biophys Acta. 1987 May 29;899(2):196-204; Biochim Biophys Acta. 1987 May 29;899(2):196-204.