Mercaptoethylguanidine (MEG) dihydrobromide 是选择性的诱导型一氧化氮合酶 (nitric oxide synthase) 抑制剂和过氧亚硝酸盐 (peroxynitrite) 清除剂。Mercaptoethylguanidine (MEG) dihydrobromide 具有用于炎症性肠病研究的潜力。

Mercaptoethylguanidine (MEG) dihydrobromide is selective inhibitor of the inducible nitric oxide synthase and peroxynitrite scavenger. Mercaptoethylguanidine (MEG) dihydrobromide has the potential for inflammatory bowel diseases research.

Mercaptoethylguanidine (MEG; 10 mg/kg i.v. b. i.d.) dihydrobromide significantly reduces the appearance of diarrhea and the loss of body weight in male rats with colitis [1]. Mercaptoethylguanidine (10 mg/kg/day; ip; for 5 days) dihydrobromide ameliorates oxidative stress parameters and antioxidant enzyme activities in forty-five Sprague-Dawley rats weighing 200 to 250 g with esophagus uninjured [2].

32665-11-5

C3H11Br2N3S

281.01

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years