X1 compound 结合抑制组蛋白 H3K27 三甲基化并阻断 X 染色体失活的起始。 X1 compound 结合减少了 RepA 的构象空间并取代了同源相互作用的蛋白质因子，包括 PRC2 和 SPEN。

X1 compound binding suppresses histone H3K27 trimethylation and blocks initiation of X-chromosome inactivation. X1 compound binding reduces the conformational space of RepA and displaces cognate interacting protein factors including PRC2 and SPEN.

T60044

C27H20N4O

416.48

X1 compound

H2O:Insoluble
DMSO:80 mg/mL(192.09 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years