FTX-6058 is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED) . FTX-6058 can induce HbF protein expression in cell and murine models. FTX-6058 can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia.

FTX-6058 inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].

2490676-18-9

C22H18FN5O2

403.41

FTX-6058

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years