产品描述
FTX-6058 hydrochloride is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED) . FTX-6058 hydrochloride can induce HbF protein expression in cell and murine models. FTX-6058 hydrochloride can be used for the research of select hemoglobinopathies, including sickle cell disease and β-thalassemia.
体外活性
FTX-6058 hydrochloride inhibits PRC2 via binding to EED, which induces robust HbF protein expression in both cell and murine models[2].
Cas No.
2490676-19-0
分子式
C22H19ClFN5O2
分子量
439.87
别名
FTX-6058 hydrochloride
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years