N1-Acetylspermidine is an acetyl derivative of spermidine that acts as a substrate for polyamine oxidase (PAO).1 In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including cell division, differentiation, and membrane function.2,3,4,5 N1-Acetylspermidine has been used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA.6

34450-16-3

C9H22ClN3O

223.74

N1-Acetylspermidine (hydrochloride);N1-Acetylspermidine hydrochloride

PBS (pH 7.2):10 mg/mL
DMSO:0.1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years