UCM05 (G28UCM) 是一种有效的脂肪酸合酶 (FASN) 抑制剂，对 HER2+ 乳腺癌异种移植物具有作用活性，且在抗 HER2 耐药细胞系中具有活性。UCM05 是一种丝状温度敏感蛋白 Z (FtsZ) 抑制剂，可抑制革兰氏阳性菌B. subtilis生长，MIC 值为 100 μM，但对革兰氏阴性菌E. coli缺乏活性。

UCM05 (G28UCM) is a potent fatty acid synthase ( FASN ) inhibitor that shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines [1]. UCM05 is a Filamentous temperature-sensitive protein Z (FtsZ) inhibitor and inhibits the growth of the Gram-positive bacterium B. subtilis with MIC values of 100 μM but lack activity on the Gram-negative bacterium E. coli [2].

1094451-90-7

C24H16O10

464.38

UCM05

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years