RR6 是竞争性的、可逆的、具有口服活性的vanin选择性抑制剂，对重组vanin-1的IC50值为540 nM。它还有效抑制人血清泛酶(IC50:40 nM)，牛血清泛酶(IC50:41 nM)和大鼠血清泛酶(IC50:87 nM)。

RR6 acts as a selective, reversible, and competitive vanin inhibitor at nanomolar concentration.

Oral administration of RR6 (3 mg/mL) in rats completely inhibited plasma vanin activity and caused alterations of plasma lipid concentrations upon fasting, thereby illustrating its potential use in chemical biology research.

1351758-37-6

C16H23NO4

293.36

RR6

DMSO:100 mg/mL (340.88 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years