COX-2-IN-23 (compound 9a) 是一种选择性的COX-2抑制剂，COX-2 和 COX-1 的IC50值分别为 0.28 和 20.14 μM。COX-2-IN-23 具有抗炎活性和低致溃疡活性。

COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC 50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.

COX-2-IN-23 (compound 9a) (9 mg/kg; a single i.p.; 0-4 hours) exhibits anti-inflammatory activities and lowest incidence of pepticulcer [1]. Animal Model: Mature male albino rats [1] Dosage: 9 mg/kg Administration: Intraperitoneal injection; 0, 1, 2, 3 and 4 hours. Result: Had similar ulcerogenic activity to celecoxib.

2417995-08-3

C24H25N5O3S2

495.62

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years