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Nadifloxacin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nadifloxacin图片
CAS NO:124858-35-1
包装与价格:
包装价格(元)
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
那氟沙星
OPC7251
产品介绍
Nadifloxacin是一种对粉刺有效的广谱氟喹诺酮类抗生素。

产品描述

Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.

体外活性

Nadifloxacin is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication. In vitro studies of nadifloxacin show potent and broad-spectrum antibacterial activity against aerobic Gram-positive, Gram-negative and anaerobic bacteria. Additionally, studies also suggest that the effectiveness of nadifloxacin in inflammatory acne lesions may be attributed to its inhibitory effect on pro-inflammatory cytokines like interleukin (IL)-1α, IL-6, and IL-8 which also play an important role in acne pathogenesis.

Cas No.

124858-35-1

分子式

C19H21FN2O4

分子量

360.385

别名

那氟沙星;OPC7251;Nadifloxacin

储存和溶解度

H2O:<1 mgml
DMSO:16 mg/mL (44.4 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years