BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI hydrochloride does not inhibit DUSP5. BCI hydrochloride is an allosteric inhibitor of dual specificity phosphatase (DUSP).

95130-23-7

C22H24ClNO

353.89

(E)-BCI hydrochloride;BCI hydrochloride

DMSO:15.62 mg/mL (44.14 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years