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16F16
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
16F16图片
CAS NO:922507-80-0
包装:50 mg
市场价:10320元

产品介绍

产品描述

16F16 is a protein disulfide isomerase (PDI) inhibitor.1It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 μg/ml.116F16 reduces PC12 cell apoptosis induced by the misfolded huntingtin protein HTTQ103. It suppresses PDI-dependent mitochondrial outer membrane permeabilization (MOMP) in isolated PC12 cell mitochondria. 16F16 (2, 3, 4, and 10 μM) reduces HTTN90Q73mutant huntingtin-induced medium spinal neuron death and MOMP in rat corticostriatal slices. It also reduces pyramidal neuron death induced by amyloid-β precursor protein (APP) in rat corticostriatal slices.

Cas No.

922507-80-0

分子式

C16H17ClN2O3

分子量

320.77

别名

16F16

储存和溶解度

DMSO:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years