(5E,9E,13E)-Teprenone is an isomer of Teprenone with antiulcer activity. It induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress.

(5E,9E,13E)-Teprenone might transiently activate the transcription of the HSP70 gene. The heat shock element-binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone.

(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa.

Animal Model: Male Wister strain rats (≈250 g). Dosage: 200 mg/kg. Administration: Oral administration

3796-63-2

C23H38O

330.55

(5E,9E,13E)-Geranylgeranylacetone;(5E,9E,13E)-Teprenone

DMSO:5 mg/mL (15.13 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years