NS2B/NS3-IN-2 是一种有效的登革病毒 (DENV)NS2B/NS3共价抑制剂，IC50为 6.0 nM ,Ki为 0.66 μM。NS2B/NS3-IN-2 无细胞毒性且能显著提高细胞存活率。

NS2B/NS3-IN-2 is a potent dengue virus ( DENV ) NS2B/NS3 covalent inhibitor with an IC 50 of 6.0 nM and K i of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate [1].

NS2B/NS3-IN-2 (compound 23) (150 nM) shows 100% inhibition rate against Dengue virus (DENV) [1]. NS2B/NS3-IN-2 (5 μM) shows no cytotoxicity and markedly increases the cell survival rate [1]. Cell Cytotoxicity Assay [1] Cell Line: Infected BHK-21 cells after DENV infection Concentration: 5 μM Incubation Time: 5 days Result: Showed no cytotoxicity and markedly increased the cell survival rate.

C24H21N3O5S

463.51

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years