LSD1-IN-21 (化合物 5a) 是一种有效的可透过血脑屏障的LSD1(赖氨酸特异性去甲基化酶 -1) 抑制剂，其IC50为 0.956 μM。LSD1-IN-21 显著降低促炎细胞因子TNF-α。LSD1-IN-21 具有良好的抗癌和抗炎活性。

LSD1-IN-21 (compound 5a) is a potent and BBB-penetrated LSD1 (Lysine specific demethylase-1) inhibitor, with an IC 50 of 0.956 μM. LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α. LSD1-IN-21 shows good anticancer and anti-inflammatory activity [1].

LSD1-IN-21 (compound 5a) shows potent anti-cancer activity with GI 50 values of 0.414 and 0.417 μM against HOP-62 and OVCAR-4 cell lines, respectively [1].

C24H25N5O2S

447.55

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years