Spaglumic Acid 是一种神经肽,在脑中以毫摩尔浓度存在。
产品描述
Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.
体外活性
Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes [1].
Cas No.
3106-85-2
分子式
C11H16N2O8
分子量
304.25
别名
N-Acetylaspartylglutamic acid;NAAG;异冬谷酸;Spaglumic acid
储存和溶解度
H2O:29 mg/mL(95.31 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years