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17-phenyl trinor Prostaglandin F2αamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
17-phenyl trinor Prostaglandin F2αamide图片
CAS NO:155205-89-3
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议

产品名称
17-phenyl trinor Prostaglandin F2α amide
产品介绍

产品描述

17-phenyl trinor Prostaglandin F2α amide (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs. Although it has been claimed that PG amides are not converted to the free acids in vivo, studies have shown that bovine and human corneal tissue converts the amides of various PGs to the free acids with a conversion efficiency of about 10-20% relative to the hydrolysis of isopropyl esters. 17-phenyl trinor PGF2α amide would be expected to show the typical intraocular effects of latanoprost, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.

Cas No.

155205-89-3

分子式

C23H33NO4

分子量

387.51

别名

17-phenyl trinor Prostaglandin F2α amide;17-phenyl trinor Prostaglandin F2α amide

储存和溶解度

Ethanol:20 mg/mL
DMF:30 mg/mL
DMSO:20 mg/mL
PBS (pH 7.2):2 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years