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CAY10747
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10747图片
CAS NO:2413849-81-5
包装:25 mg
市场价:13303元

产品介绍

产品描述

CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex and the Hsp90-Cdc37 clients phosphorylated Akt and Cdk4 in A549 cells when used at a concentration of 5 μM. CAY10747 inhibits proliferation of A549, MCF-7, HOS, and HepG2 cells (IC50s = 0.41, 0.64, 0.9, and 0.94 μM, respectively) and induces apoptosis in A549 cells.

Cas No.

2413849-81-5

分子式

C42H48FNO6

分子量

681.83

别名

CAY10747

储存和溶解度

DMSO:20 mg/mL
Ethanol:1 mg/mL
DMF:30 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years