RIPK3-IN-2 是RIP3抑制剂。RIPK3-IN-2 可用于由激活的坏死途径引起或与之相关的疾病研究。

RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research [1].

RIPK3-IN-2 (0.3-20 μM; 42 h) inhibits HT-29 cell growth [1]. RIPK3-IN-2 (0.3-20 μM; 14 h) inhibits MEF cell growth [1]. RIPK3-IN-2 (0.3-20 μM; 18 h) inhibits L929 cell growth [1]. Cell Viability Assay [1] Cell Line: HT-29 cells Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM Incubation Time: 42 hours Result: Showed EC 50 value of 0.085 μM. Cell Viability Assay [1] Cell Line: MEF cells Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM Incubation Time: 14 hours Result: Showed EC 50 value of 0.24 μM. Cell Viability Assay [1] Cell Line: L929 cells Concentration: 0.3, 1.0, 3.0, 10.0, 20.0 μM Incubation Time: 18 hours Result: Showed EC 50 value of 0.21 μM.

2665669-32-7

C21H16ClN3O2S2

441.95

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years