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Valorphin TFA(144313-54-2(free base))
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Valorphin TFA(144313-54-2(free base))图片
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
Valorphin TFA(144313-54-2(free bas))
产品介绍
Valorphin TFA(144313-54-2(free bas)) 是具有 opioid 类镇痛活性的二氢戊酸的半合成衍生物。

产品描述

Valorphin TFA is a semisynthetic derivative of dihydrovaltrate with opioid analgesic activity

体外活性

In vitro binding studies using brain homogenates from rat and guinea-pig indicate a preference for the mu-receptor site.?Bath application to cultured cerebellar Purkinje cells inhibited the spontaneous firing, similar to the effect seen with morphine.?Analgesic activity has been demonstrated in the hot plate and the tail flick test in the mouse and the Randall-Selitto test in the rat.?In the rhesus monkey valorphin was self-administered, but naloxone challenge induced only mild withdrawal signs.?Valorphin is a novel chemical entity, structurally not related to known opioids, which interacts preferentially with opiate mu-receptors[1].

Cas No.

T7666

分子式

C46H62F3N9O13

分子量

1006.03

别名

Valorphin TFA(144313-54-2(free bas));Valorphin TFA(144313-54-2(free base))

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years