CDK5-IN-3 (化合物 11) 是一种有效和选择性的CDK5抑制剂,抑制CDK5/p25和CDK2/CycA的IC50值分别为 0.6 nM 和 18 nM。CDK5-IN-3 可用于常染色体显性遗传多囊肾病 (ADPKD) 的研究。
产品描述
CDK5-IN-3 (compound 11) is a potent and selective CDK5 inhibitor, with IC 50 s of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. CDK5-IN-3 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD) [1].
Cas No.
2639542-32-6
分子式
C22H26N4O
分子量
362.47
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years