GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated with congestive heart failure.

1419609-94-1

C25H28N6O3

460.53

GSK2798745

DMSO:250 mg/mL (542.85 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years