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AM12
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AM12图片
CAS NO:2387510-84-9
包装:5 mg
市场价:7000元

产品介绍

产品描述

AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).

体外活性

AM12 also inhibits TRPC5 activity evoked by the agonist (-)-Englerin A. AM12 also inhibits TRPC4 channels similarly. AM12 inhibits TRPC5 and TRPC4 channels via a site accessible from the extracellular face of the membrane, acting directly on either the channel or a site closely associated with it. AM12 also inhibits Ca2+ entry evoked by Gd3+. AM12 inhibits the Gd3+-evoked Ca2+ signal (IC50: 0.28 μM). AM12 is slightly more potent than the natural product Galangin as an inhibitor of the Gd3+-evoked signal.

Cas No.

2387510-84-9

分子式

C15H9BrO5

分子量

349.13

别名

AM12

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years