DM1-SMe 是美登木素微管的有效抑制剂。 DM1-SMe 的效力是母体药物美登素的 3 至 10 倍，在一组人类肿瘤细胞系中，DM1-SMe 的 IC50 为 0.003 至 0.01 nM。

DM1-SMe is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines.

138148-68-2

C36H50ClN3O10S2

784.38

DM1-SSMe;DM1-SMe

DMSO:Soluble
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years