Smo-IN-2 (compound 1) 是一种有效的Smoothened (Smo)抑制剂，对 hedgehog (Hh) 信号通路的IC50为 123.4 nM。Smo-IN-2 对人髓母细胞瘤细胞系 Daoy 有抗增殖作用。具有抗癌活性。

SMO-IN-2 (compound 1) is a potent smoothened (SMO) inhibitor with an IC 50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity [1].

SMO-IN-2 (compound 1) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC 50 of 0.51 μM [1].

1822355-27-0

C25H25F4N5O2

503.49

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years