HIV-1 inhibitor-21 (compound 9b) 是一种有效的HIV-1非核苷逆转录酶 (RT) 抑制剂，对 HIV-1 RT 的IC50为 0.55 μM。HIV-1 inhibitor-21 对野生型 HIV-1 和突变病毒株 K103N 具有抗逆转录活性，EC50分别为 12.7 nM 和 10.4 nM，同时具有相对较低的细胞毒性 (MT-4 CC50=10.2 μM)。

HIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC 50 value of 0.55 μM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC 50 s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4 cells CC 50 =10.2 μM) [1].

2554620-04-9

C28H24N6O2

476.53

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years