Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3 μM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis.

678158-55-9

C22H23N3O2S

393.5

Mcl1-IN-8

DMSO:50 mg/mL (127.06 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years