VK-II-86 是一种非β-阻断卡维地洛类似物。它可以防止哇巴因诱导的心脏毒性。

VK-II-86 is a non-β-blocking carvedilol analog. It prevents ouabain-Induced cardiotoxicity

VK-II-86 are effective to prevent ouabain-induced apoptosis and spontaneous contractions indicative of arrhythmogenic activity without affecting inotropy and demonstrated to be effective in human models, thus emerging as a therapeutic tool for the prevention of digitalis-induced arrhythmias and cardiac toxicity[1].

955371-84-3

C25H28N2O4

420.509

VK-II-86

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years