1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility. Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.

22002-85-3

C19H39O7P

410.48

1-Palmitoyl Lysophosphatidic Acid

DMF:2 mg/mL
PBS (pH 7.2):3 mg/mL
DMSO:2.5 mg/mL
Ethanol:25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years