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Eperezolid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eperezolid图片
CAS NO:165800-04-4
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
PNU-100592
产品介绍
Eperezolid是一种在体外表现出良好抑制活性的恶唑烷酮类抗生素。

产品描述

Eperezolid is an oxazolidinone antibacterial agent. Eperezolid showed well in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml).

体外活性

The specific binding of eperezolid is dose-dependent and is proportional to the ribosome concentrations. The binding of eperezolid to the ribosome is competitively inhibited by chloramphenicol and lincomycin. However, unlike chloramphenicol and lincomycin, eperezolid does not inhibit the puromycin reaction, indicating that the oxazolidinones have no effect on peptidyl transferase [2]. Antibiotic Eperezolid binds specifically to the 50S ribosomal subunit of Escherichia coli. eperezolid was found to bind only to the 50S subunit, with similar affinity as to the 70S ribosome, and to have no affinity for the 30S subunit [3].

Cas No.

165800-04-4

分子式

C18H23FN4O5

分子量

394.4

别名

PNU-100592;Eperezolid

储存和溶解度

DMSO:44 mg/mL (111.56 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years