PP7 是一种PB1-PB2互作抑制剂，IC50为 8.6 μM。PB1-PB2 抑制病毒聚合酶的活性，IC50为9.5 μM。它对甲型流感病毒 A 包括 (H1N1)pdm09 (EC50=1.4 μM)，A(H7N9)，A(H9N2) 亚型具有抗病毒活性。

PP7 is a potent inhibitor of PB1-PB2 interaction(IC50 of 8.6 μM).

PP7 showed inhibition against viral polymerase activity (IC50=9.5 μM). PP7 exhibited antiviral activities against influenza virus subtypes A (H1N1)pdm09(EC50=1.4 μM), A(H7N9) and A(H9N2) in cell cultures[1].

433238-84-7

C18H14Cl2N2O3

377.22

PP7

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years