SENP1-IN-4 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 21. SENP1-IN-4 is developed for tumor radiosensitivity enhancement.

SENP1-IN-4 improves the sensitivity of tumor cells to irradiation[1]. SENP1-IN-4 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC 50 of >20 μM[1]. Cell Cytotoxicity Assay[1]Cell Line: Hela cells Concentration: 0.7 μ M, 2.2 μM, 6.6 μM、20 μM Incubation Time: 72 hours Result: IC 50 >20 μM

2416910-64-8

C33H54N2O3

526.806

SENP1-IN-4;SENP1-IN-4

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years