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TMRM Perchlorate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TMRM Perchlorate图片
CAS NO:115532-50-8
包装与价格:
包装价格(元)
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
四甲基若丹明甲酯酸铵
T668
产品介绍
TMRM Perchlorate 是细胞渗透性的阳离子亲脂性红色荧光染料 (λex=530 nm, λem=592 nm)。

产品描述

TMRM Perchlorate is a cell-permeant cationic lipophilic red fluorescent dye (λex=530 nm, λem=592 nm).

体外活性

TMRM Perchlorate is a fluorescent probe (excitation, 530±21 nm; emission, 592±22 nm). The fluorescence signal in the presence of TMRM Perchlorate shows a slight decrease after the addition of glutamate, indicative of increased polarization of the mitochondrial inner membrane. In the presence of TMRM Perchlorate (2 μM) the coupled respiration with Complex I substrates or upon the addition of Complex II substrate is decreased by 27%[1]. Exposure of hippocampal cultures to low concentrations of TMRM Perchlorate (50 to 500 nM) for 1 to 3 hours results in selective staining of mitochondria in both neurons and the underlying glial cells. Exposure of hippocampal cultures to high concentrations of TMRM Perchlorate (1 to 25 μM) stains mitochondria selectively and quickly, reaching a plateau after 5 to 10 min. Low concentrations of TMRM Perchlorate (50 to 200 nM) do not induce apoptosis, whereas higher concentrations (0.5 and 2.5 μM) enhance apoptosis (KD?=?500 nM)[2].

Cas No.

115532-50-8

分子式

C25H25ClN2O7

分子量

500.93

别名

四甲基若丹明甲酯酸铵;T668;TMRM Perchlorate

储存和溶解度

DMSO:41.67 mg/mL (83.19 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years