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As-358
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2222042-47-7
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
As-358 对埃博拉病毒 (Ebola virus) 和马尔堡病毒 (Marburg virus) 具有抑制活性,IC50分别为 47.5 μM 和 3.7 μM。

产品描述

As-358 has inhibitory effects against Ebola virus and Marburg virus, with IC 50 s of 47.5 μM and 3.7 μM [1].

体外活性

As-358 (compound 3b) (0-500 μM; 10 days) exhibits inhibitory activities against EBOV and MARV [1]. As-358 (0-100 μM; 48 hours) can inhibit WT-EboV-GP and mutant D522A-EboV-GP, with IC 50 s of 1.7 and 2.2 μM, respectively [1]. Cell Proliferation Assay Cell Line: Vero (infected with EBOV and MARV) [1] Concentration: 0-500 μM Incubation Time: 10 days Result: Exhibited inhibitory activities against EBOV and MARV, with IC 50 s of 47.5 ± 8.2 μM and 3.7 ± 1.7 μM, SI values of 9 and 118, respectively.

Cas No.

2222042-47-7

分子式

C18H31NO2

分子量

293.44

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years