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IM156 acetate(HL156A HL271 acetate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IM156 acetate(HL156A HL271 acetate)图片
CAS NO:1422365-94-3
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

IM156 (also known as HL-156A) is a metformin derivative thac acts as a novel and highly potent AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model.

References:

[1].Row H, et al. HL271, a novel chemical compound derived from metformin, differs from metformin in its effects on the circadian clock and metabolism. Biochem Biophys Res Commun. 2016 Jan 15;469(3):783-9.

[2].Bang E, et al. The Improving Effect of HL271, a Chemical Derivative of Metformin, a Popular Drug for Type II Diabetes Mellitus, on Aging-induced Cognitive Decline. Exp Neurobiol. 2018 Feb;27(1):45-56.

[3].Sun Young Rha, et al. Phase I study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 38(15_suppl):3590-3590.

Related CAS #:1422365-94-3 (acetate) 1422365-93-2 (free base) 1422365-52-3 (HCl) 2043654-64-2 (TFA) 2043654-70-0 (malonate) 2043654-72-2 (furmate) 2043654-97-1 (tosylate) 2043654-98-2 (mesylate)

纯度:≥98%

CAS:1422365-94-3